One benefit of running it on a real homeserver (as opposed to cloud) is that cloudflare bot protection is less hostile to my home IP.
I'm running off a home NAS. Half the indexers are blocked by Cloudflare, but the useful ones all seem to work. Readarr can't seem to find any files though. I threw in some comics as a tester and it found all the volumes and metadata but no files.
@jackerhack @nemo @karthikb351 running it off my NAS here as well, since about a year now. https://sathyabh.at/2023/01/21/asustor-lockerstor4-as6604t/